Vurdon SR

Diclofenac Sodium
100 mg SR Capsule

Vurdon SR (Diclofenac Sodium) is a potent non-steroidal anti-inflammatory drug (NSAID) with pronounced anti-rheumatic, anti-inflammatory, analgesic and antipyretic properties. It has also some uricosuric effect. Diclofenac exerts its effect by inhibiting prostaglandin biosynthesis which plays a major role in causing inflammation, pain and fever. Diclofenac is rapidly and completely absorbed from the gastro-intestinal tract when taken with or after meal. Peak plasma concentrations are reached within an average of 2 hours after ingestion of it. At therapeutic concentrations, it is 99.7% bound to plasma proteins. Diclofenac is metabolized in the liver and undergoes first-pass metabolism.

  • Composition

    Each capsule contains Diclofenac Sodium BP 100 mg as sustained release pellets.
  • Indication

    It is indicated for
    1. the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis, ankylosing spondylitis.

    2. non-articular rheumatism, acute musculoskeletal disorders and back pain.

    3. painful syndromes of the vertebral column

    4. acute gout.

    5. painful post-traumatic and post operative inflammation and swelling such as dental or orthopedic surgery.

    6. painful inflammatory conditions in gynaecology and primary dysmenorrhoea.

    7. in fever and pain associated with inflammatory infections of the upper respiratory tract.
  • Dosage & Administration

    One capsule daily, preferably at meal times or, as directed by the physician.
  • Contraindication

    It is contraindicated in known hypersensitivity to Diclofenac or other non-steroidal anti-inflammatory drugs to patients with active peptic ulcer and to patients in whom aspirin induced asthma, acute rhinitis and urticaria were observed.
  • Precaution

    It should be used cautiously in patients with a history of cardiovascular disease, in patients with a history of gastro-intestinal disease or bleeding and in patients with severe hepatic or renal damage, asthma etc.
  • Side Effects

    Generally, it is well tolerated. The common side effects include- gastro-intestinal discomfort, bleeding, nausea, vomiting, dizziness, headache, jaundice, insomnia, drowsiness, depression, anxiety, urticaria, hypersensitivity reactions (bronchospasm, angioneuratic edema, rashes) and hearing disturbances such as tinnitus.
  • Drug Interaction

    Various non-steroidal anti-inflammatory agents are liable to inhibit the activity of diuretics. Concomitant treatment with potassium sparing diuretics may be associated with increased serum potassium levels, making it necessary to monitor these levels. Patients taking Diclofenac and also receiving digoxin, methotrexate, cyclosporine or lithium should be observed for potential development of the specific toxicities of these drugs. Concomitant administration of other systemic non-steroidal anti-inflammatory agents or glucocorticoids may increase the occurrence of side effects e.g. gastrointestinal bleeding.
  • Overdose

  • Pregnancy & Lactation

    The use of Diclofenac should be avoided in pregnancy and lactation unless the potential benefits to the other outweigh the possible risks to the fetus.
  • Storage Condition

    Keep in a dry place away from light and heat. Keep out of the reach of children.
  • How Supplied

    Each box contains 50 capsules in Alu-PVDC blister pack.