150 mg Tablet & 75 mg/5 ml Syrup

Gastab (Ranitidine) is a H2-receptor (histamine) antagonist. It is a competitive, reversible inhibitor of the action of H2-receptors, on the parietal cells. As a result of its H2-receptor blocking action, Gastab promotes rapid and effective ulcer healing with sustained pain relief both day and night by a reduction of gastric acid output. After oral administration, Ranitidine is rapidly absorbed from gastrointestinal tract. It is widely distributed throughout the body and is 10-19% protein bound. It is metabolized in the liver and excreted principally through urine.

  • Composition

    Gastab Tablet : Each film coated tablet contains Ranitidine Hydrochloride USP equivalent to Ranitidine 150 mg.

    Gastab Syrup : Each 5 ml syrup contains Ranitidine Hydrochloride USP equivalent to Ranitidine 75 mg.

  • Indication

    1. Short-term treatment of active duodenal ulcer.

    2. Maintenance therapy for duodenal ulcer patients at reduced dosage after healing of acute ulcer.

    3. Treatment of pathological acid hypersecretory conditions (e.g. Zollinger-Ellison Syndrome and systemic mastocytosis).

    4. Short-term treatment of benign gastric ulcer.

    5. Treatment of reflux esophagitis and erosive esophagitis.

  • Dosage & Administration

    Adult Dose :
    Gastric and duodenal ulcer : 150 mg twice daily in the morning and at night or 300 mg as a single dose at night for 4 to 8 weeks. 150 mg at night is used as maintenance therapy.

    Reflux esophagitis : 150 mg twice daily or 300 mg as a single dose at night for 8 to 12 weeks.

    Zollinger-Ellison Syndrome : 150 mg 3 times daily and this may be increased if necessary to 6 gm daily in divided doses up to 6 weeks.

    Children Dose : 2-4 mg/kg body weight twice daily.
  • Contraindication

    Ranitidine is contraindicated in patients who have known hypersensitivity to this drug.
  • Precaution

    Ranitidine should be given in reduced doses to patients with impaired renal and hepatic function.
  • Side Effects

    Side effects of Ranitidine are generally infrequent and minor. Headache, dizziness, constipation, nausea, abdominal pain and rash may occur by using this drug.
  • Drug Interaction

  • Overdose

  • Pregnancy & Lactation

    US FDA Pregnancy Category of Ranitidine is B. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Ranitidine have been shown to be excreted in human milk. So, caution should be exercised when Ranitidine is administered to a nursing woman.
  • Storage Condition

    Keep in a dry place away from light and heat. Keep out of the reach of children.
  • How Supplied

    Gastab Tablet : Each box contains 20 tablets in Alu-Alu blister pack.

    Gastab Syrup : Each amber PET bottle contains 100 ml syrup.